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Individuals already taking GLP-1 receptor agonists for diabetes or weight management should continue their prescribed therapy as directed, but should not expect guaranteed cognitive benefits beyond those associated with improved metabolic health

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Metabolic pathway requiring 5-deoxyadenosylcobalamin The figure illustrates the metabolic pathway for the vitamin B 12 -dependent enzyme L-methylmalonyl-CoA mutase, which converts L-methylmalonyl-CoA into succinyl-CoA for entry into the citric acid cycle

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3 Examples: E11.21 E11.22 + additional CKD stage code (N18.-) E11.3- (specify type: mild, moderate, severe, proliferative) E11.40E11.49 4 & add .65 (e.g., E11.65 = Type 2 with hyperglycemia) add .64 (specify with or without coma) 5 1