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Unlike statins, which predominantly lower LDL cholesterol, semaglutide functions differently by influencing weight reduction and glycemic controlfactors indirectly beneficial to heart health

The NDA submission was partly based on topline results from the ongoing single location BHV4157-206-RWE study (NCT06529146), in which troriluzole 200 mg administered orally once daily led to a 5070% slower rate of decline from baseline in the functional Scale for the Assessment and Rating of Ataxia (f-SARA) in all SCA genotypes at 3 years compared to an external control arm. Data from the BHV4157-206 study (NCT03701399) also demonstrated disease stabilization in the SCA3 genotype and a reduction in falls in all SCA genotypes compared to placebo over 48 weeks. If approved, troriluzole will be the first and only medication indicated for the treatment of SCA

doi: 10.1111/dom.14843, 53 GibbonsC.BlundellJ.Tetens HoffS.DahlK.BauerR.BaekdalT

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Common side effects include gastrointestinal symptoms (nausea, vomiting, diarrhoea), decreased appetite, fatigue, and injection site reactions

Catgorie Sant: Indication: Les capsules de L-Carnitine sont un complment alimentaire contenant l'acide amin L-carnitine, qui joue un rle cl dans le mtabolisme nergtique, la combustion des graisses et la gestion du poids