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Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD et al

Additional studies have highlighted the neuroprotective effects of other natural compounds, such as benzyl ITC and indole-3-carbinol (not an ITC, but derived from indole glucosinolates), in preclinical models of PD

In order to formally demonstrate the role of the C596-U597 disulfide, the 597 residue was mutated to a serine (U597S) and we characterized the effect of this change on the reductive half-reaction