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Unveiling novel biomarkers: a clinical study of miR-146a and miR-222 in the diagnosis and treatment of polycystic ovary syndrome

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In terms of glycemic control, these agents affect glucose metabolism through distinct pathways: GLP-1RAs enhance glycemic control by stimulating glucose-dependent insulin secretion, while SGLT2is lower blood glucose levels by inhibiting glucose reabsorption in the proximal renal tubules, leading to increased urinary glucose excretion

However, those treated with GLP-1 RAs appear to have higher prevalence of late-diabetic complications and previous SU and insulin use

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