Five half-lives (roughly 5 weeks) covers near-complete elimination, and the 2-month buffer adds a safety margin for patients who are actively attempting conception
Side Effects The most common side effects caused by Orlistat include stomach or rectal pain, diarrhea, oily spotting, fatty or oily stool, intestinal gas with oily discharge, urgent bowel movement, increased bowel movements, poor bowel control, itching, loss of appetite, lethargy, dark-colored urine, clay-colored stools, or jaundice
Not really, and that's the point
Association between Hypothyroidism and Small Intestinal Bacterial Overgrowth
You're not happy
doi: 10.1007/s00394-021-02770-2 22 MaratheCSRaynerCKJonesKLHorowitzM