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Some frameworks suggest that the interaction of these peptides could influence intracellular mediators relevant to receptor activation and downstream transcriptional regulators
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Pharmacol Biochem Behav 163:5765 Tomaz V, Chaves Filho A, Cordeiro R, Juc P, Soares M, Barroso P, Cristino L, Jiang W, Teixeira A, de Lucena D, Macedo D (2020) Antidepressants of different classes cause distinct behavioral and brain pro- and anti-inflammatory changes in mice submitted to an inflammatory model of depression
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Results become noticeable within a few weeks, with full effects visible after a couple of months
J Hepatol 2023;79:155765.ArticlePubMed 12
