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In real-world tolerance tests, a repeat-insult patch test on an eye lotion with 0.2% Centella extract showed no irritation or allergic contact dermatitis in 54 subjects

limited efficacy data, variable absorption

Colorectal cancer (2020)

Niemiec A, Stasiak U, Wasilewska A, Przybylski D, Marchelek-Myliwiec M, Nowosiad-Magda M (2020) Multi-faceted function of vitamin K with particular consideration of vitamin K2literature review

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The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product