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This heritage has given us experience and capabilities that also enable us to drive change to help people defeat other serious chronic diseases such as obesity, rare blood, and endocrine disorders
Modifications of active site thiol groups by two redox-dependent aberrant post-translational modifications, S-glutathionylation and S-nitrosylation, lead to inactivation of the normal enzymatic activity of PDI (Walker et al., 2010)
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The minimum panel should include a CBC (to check hemoglobin and red blood cell indices), ferritin (to assess iron stores), and ideally serum iron and total iron-binding capacity (TIBC) for a more complete picture
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