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Molecular bases of incretin system Synthesis and distribution of GLP-1 GLP-1, GLP-2, and glucose-dependent insulinotropic polypeptide (GIP) are the predominant gut-derived incretin hormones that lead to postprandial insulin secretion in a glucose-dependent fashion
Some common side effects of spironolactone include: Breast tenderness Dizziness Drowsiness Dry mouth Enlarged breast tissue in men (gynecomastia) Headache Irregular menstrual periods Post-menopausal vaginal bleeding Stomach upset, vomiting, and diarrhea More severe side effects include: Arrhythmia Confusion Decreased urination Difficulty breathing or swallowing Flu-like symptoms Muscle pain or weakness Numbness or tingling Serious skin reactions Unusual bleeding or bruising Though it may help in specific cases, spironolactone is not a weight-loss drug
Doctors often advise patients to stop blood-thinning medications before a colonoscopy to minimize bleeding, but semaglutide does not act as a blood thinner
Are GLP-1 Pills as Good as the Shots
For a deeper dive into the muscle loss data and complete lean mass protection strategy, see my GLP-1 muscle loss guide