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What the Clinical Trial Evidence Shows Phase 2 trials published in NEJM (2023) reported dose-dependent mean resting heart rate increases of approximately 57 bpm at higher doses

The result can be increased shedding several months after beginning treatment or experiencing significant weight loss

A novel class of incretin-based therapies consisting of glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) and dual (GLP1/glucose-dependent insulinotropic polypeptide [GIP]) RAs acts by lowering blood sugar and inducing weight loss

difficile infection (watery diarrhea three or more times daily, fever, abdominal cramps, or diarrhea persisting after antibiotics end)

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