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Do not combine topical GHK-Cu with strong acids (low-pH vitamin C, AHAs, BHAs) in the same application because pH conflict can destabilize the peptide
Muizzuddin N, Benjamin R
Route and formulation change exposure, metabolism and safety
In this binding mode, hydrogen bonds of Tyr111 and Gln207 to the carbonyl oxygen atoms of 4HNE, NE, and EA could orient the substrates and enhance their electrophilicity to promote conjugation with glutathione
Ward ZJ, Bleich SN, Long MW, et al
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