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Inspection of the trajectory of weight changes with time revealed that weight loss continued to progress in the CagriSema group up to the end of treatment at 32 weeks, whereas in the semaglutide and cagrinlitide groups, weight reduction seemed to approach a plateau [10]

This reduction in food intake naturally raises concerns about nutritional deficiencies, including B12

Eur J Nutr [Internet]

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In addition, its thiol grouping binds with heavy metal salts (mercury, lead, cadmium...) enabling them to be safely excreted by the body (4)