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Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine (TMA) and trimethylamine-N-oxide (TMAO), since these metabolites are normally excreted in the urine

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It was reported that NSAID usage varies with both sex and age [20, 21], and since sex hormones can affect various physiological responses, we divided the subjects into eight groups based on sex, age, and NSAID usage

Additionally, L-carnitine has been shown to reduce fatigue and improve mental focus, which can make it easier to stick to a weight loss program