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Random-effects models were implemented, and restricted maximum likelihood (REML) estimation was used to estimate the variance between studies and to produce pooled effect sizes of each outcome
Study: The No-Hunger Games: How GLP-1 Medication Adoption is Changing
In simple terms: your liver doesnt just get tiredits ability to maintain metabolic balance may gradually wear down without proper circadian alignment
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Temporelli PL et al
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