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Participants taking retatrutide 4 mg, 9 mg, and 12 mg lost an average of 29.8 lbs (12.7%), 45.4 lbs (19.1%), and 49.6 lbs (20.8%), respectively, alongside A1C reductions of up to an average of 1.6%
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STEP Trials: These trials focused on the weight loss benefits of Semaglutide, but also noted improvements in kidney outcomes, particularly in overweight individuals with diabetes
doi:10.1016/S2213-8587(21)00174-1 American Diabetes Association Professional Practice Committee
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