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doi: 10.1007/s00210-024-03539-0 62 WonCSOberliesNHPaineMF

Continuous administration does not seem to provide additional benefit and may actually diminish the compound's effectiveness over time

Published 2023 Apr 13

Moffat et al., 1996

The absence of this test is not automatically disqualifying for every research context, but it is information a serious researcher should factor into their assessment