Other current treatments such as penile injections function to temporarily increase penile blood flow, a transient solution at best [10, 11, 12]
Current medical management for all three conditions is based on attempts to find solutions from approved symptomatic medications, and while it is positive that women can be offered some options to deal with symptoms that severely impact their quality of life, these repurposed drugs and biologics offer only a band-aid solution, with none addressing the conditions underlying causes
Sigma-1 receptor activation induces autophagy and increases proteostasis capacity in vitro and in vivo
129 Stress, anxiety, and depression are known to be associated with changes in pain sensitivity, GI motility, and intestinal permeability via a complex network that connects the GI tract, brain, immune system, and microbiota
New England Journal of Medicine , 385(6), 503-515
This direct contact may enhance local tissue effects beyond what systemic administration achieves