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Not necessarily, because the side effects come from the drug rather than how you take it
It was previously thought that eating seeds, nuts, and corn could lead to diverticulitis
only one study had a follow-up greater than 1 year
doi: 10.1016/j.freeradbiomed.2010.01.006 101 GiustariniD.TsikasD.ColomboG.MilzaniA.Dalle-DonneI.FantiP.et al
A unique finding is dysesthesia (tingling/altered sensation) in 20.9% at 12mg in TRIUMPH-4 and 12.5% in TRIUMPH-1
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