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The strategies to address senescent cells and replenish exhausted stem cells during the aging process, as well as supplementing metabolic substances like NAD+, gene therapy, or epigenetic approaches to mitigate aging, are different because they aim to promote the repair of senescent cells rather than inducing their apoptosis (Covarrubias et al., 2020

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Pressure equilibration was allowed for 30 s following injection to avoid backflow

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10.1038/s41598-018-33964-0 248 NaumannM.PalA.GoswamiA.LojewskiX.JaptokJ.VehlowA.et al

Periodic inventory reconciliation keeps expired or depleted lots from entering active workflows