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Neidlein, S., Wirth, R., & Pourhassan, M

(2021) demonstrated that MOTS-c levels decline with age in both mice and humans, and that exogenous MOTS-c administration improved physical capacity in aged mice without observable toxicity over a 2-week treatment window [5]

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This analysis, which may provide a rational judgment on the physicochemical space to optimize oral bioavailability, will be discussed

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