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Abstract Glutathione-mediated biotransformation in the liver is a well-known detoxification process to eliminate small xenobiotics, but its impacts on nanoparticle retention, targeting and clearance are much less understood than liver macrophage uptake, even though both processes are involved in liver detoxification

Mir Vinyals (University of Zurich) for providing us with purified roGFP1-iE protein

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3.1.4 Supercritical fluid extraction method Supercritical fluid extraction is an alternative two-step technique

This complete, ready-to-use kit includes black 96-well plate(s), glutathione reductase standard (200 mU/mL), glutathione reductase substrate, and other components to perform the assay

The trans effect determines the polarizability of the CoC bond so formed