Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29
Deficiency concerns: Alcoholism intestinal and bariatric surgeries digestive disorders lack of intrinsic factor vegetarians Vegans who do not consume any animal products When you don't have enough folate and vitamin B12, deficiency can result in anemia, fatigue, irregular heartbeat, shortness of breath, hair loss, and pale skin with mouth sores
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Bioelectrochemistry Bioenerg (1997) 42:14152
For laboratory handling it is typically reconstituted with a compatible solvent such as bacteriostatic water before use in non-clinical assays