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Cardiac work cost of sustained heart-rate elevation quantified as rate-pressure product (heart rate systolic pressure), the standard index of myocardial oxygen demand, not as a calorie figure
Most compounding pharmacies and research suppliers recommend starting with 25-50mg daily and increasing to 50-100mg based on tolerance and perceived effects
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This selectivity was demonstrated in animal models and has not been fully characterized in long-term human studies
Giordano, S
Meyer, A
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