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Her dose increased by 0.1 mg until she reached 0.6 mg
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This can lead to reduced expression of GLP- 1 receptors and the development of GLP- 1 resistance
Against this backdrop, glucagon-like peptide-1 receptor agonists (GLP-1 RAs), first used for type 2 diabetes, have emerged as potent weight-loss agents with possible anti-inflammatory actions, making them attractive candidates in HS care
But the FDA's briefing documents flagged it as an uncharacterized risk requiring further investigation before any approval, and researchers continue to weigh the angiogenic mechanism against the compound's apparent safety profile in animal models