More Serious Issues: In rare cases, particularly with high, unsupervised doses or pre-existing health problems, there are reports of liver or kidney issues
doi: 10.1159/000119226 52 KuratsuneHYamagutiKLindhGEvengardBTakahashiMMachiiTet al
2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes
Getting the reconstitution and dose right matters, but it is only one piece of the picture
A recent in vivo study in healthy subjects showed that acute intravenous infusion of GLP-1 during a pancreatic clamp, in which insulin and glucagon levels were maintained at basal levels, caused a reduction in hepatic glucose production, suggesting a potential direct effect on gluconeogenesis [11]
Use gentle, upward strokes and avoid the immediate eye area unless the product is specifically formulated for that delicate region