3b,c and Extended Data Fig
This happens with all glucocorticoid formulations metabolized by cytochrome P450 3A4 regardless of route of administration: oral, injectable, intra-articular, and even inhaled and intranasal formulations
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Allow the skin to return to room temperature if refrigerated medication is used, as cold injections are more painful
The reconstitution calculator handles this optimization automatically, letting you input your target units and vial size to get the optimal water volume
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