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Your dermatologist may also recommend an over-the-counter pain medication, such as ibuprofen or acetaminophen, to address any acute pain

Payne, C., Wiffen, P

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This expansion is especially important because emerging observational evidence has already shown that GLP-1 receptor agonist exposure may be associated not only with altered symptom trajectories, but also with differences in major joint injections and conversion to arthroplasty in patients with preexisting OA, underscoring the need for future trials to capture pathway-level outcomes rather than pain alone (Porto et al., 2025)

Consult Your Healthcare Provider: If constipation persists or becomes bothersome, don't hesitate to discuss it with your healthcare provider

Enrolled participants had a mean baseline A1C of 8.1% in both treatment groups