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What Mitochondria Do Mitochondria are tiny power plants inside nearly every cell

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The development of gene editing tools has evolved from homologous recombination to first-generation zinc finger nucleases (ZFNs), second-generation transcription activator-like effector nucleases (TALENs), and the more recent clustered regularly interspaced short palindromic repeats (CRISPR)-associated system, which has revolutionized life sciences 97

While some of them are characteristically up-regulated, the others are down-regulated at the same time (Texeira et al., 2006