Current 2D models are very limited and physiologically inaccurate, and the data obtained from them may not translate to the in vivo setting, ultimately delaying the advancement of knowledge in this field
doi: 10.1007/s40272-020-00410-6 406 Tan-LimCSCEsteban-IpacNARRectoMSTCastorMARCasis-HaoRJNanoALM
Diabet Med 1994
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Paolisso G, Gambardella A, Tagliamonte MR, Saccomanno F, Salvatore T, Gualdiero P, DOnofrio MV, Howard BV
And you can solve that problem with adding a little bit of T3 or balancing those hormones and then later removing it and seeing if they can get by on their own