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Storage Publications (7) Journal Impact Factor Most Recent Nat Commun Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system

The model could be relevant to address limitations of conventional animal models and could prove useful to detect undesirable drug adverse events to avoid unnecessary animal suffering during preclinical testing

The treatments effectiveness is underlined by its ability to initiate noticeable changes shortly after the procedure

In particular, we will discuss the impact of metabolic disorders in affecting HF and cognitive function, and the implication of clinical treatments, focusing on paramount effects of new antidiabetic drugs