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Brand-name Ozempic and Wegovy are manufactured by Novo Nordisk in FDA-approved facilities with FDA-reviewed labeling, and typically come in prefilled pens
All GLP-1 medications carry a black-box warning regarding a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2), making pre-treatment screening essential
Individuals under 18, pregnant or nursing individuals, or those with active medical conditions - per the brand's own label caution, physician consultation is recommended before use in these groups
New or worsening inflammatory bowel disease, including Crohns disease or ulcerative colitis, has been reported with medicines that affect IL-17 pathways
Semaglutide and tirzepatide are often talked about in the same breath because they both help with weight loss and blood-sugar controlbut there are some important differences