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Genetic factors influence how your body responds to semaglutide
This makes them the only effective option for many people with malabsorption issues
As a GLP-1 receptor agonist, semaglutide works by mimicking glucagon-like peptide-1, a naturally occurring hormone involved in appetite regulation and metabolic control
As there is no meaningful expression of GLP-1 receptors on hepatocytes, the major effect of GLP-1 agonists on MASH is likely to be indirect and may be related to a reduction in calorie intake, body weight and insulin resistance, all of which would lead to reduced liver lipid accumulation and hepatic inflammation 7,8
Once there, they can be oxidized (used as fuel)
Contrave: This medication, which combines naltrexone and bupropion, works to suppress appetite and support weight loss
