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The activation of NK cells is not only inhibited by TAMs, but also by myeloid-derived suppressor cells (MDSCs), which are heterogeneous cells derived from the bone marrow with potent immunosuppressive activity that can migrate to peripheral lymphoid organs or tumors, promote the formation of TME

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Consequently, 400600 peptides are currently being reviewed for the treatment of various ailments, including cancer (4)

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