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N-Acetylcysteine (NAC)

and actually SARS-CoV-2 causing COVID-19, all are characterized by persistent inflammation, continuous production of reactive oxygen/nitrogen species and oxidative stress that predominate over the antioxidant defenses (GSH and free radical scavenger enzymes) resulting in cell/tissue/organ aging associated with early (premature) chronic inflammation/inflammaging. We propose that, although inflammaging was introduced for the aging process (276289), it could also apply to early (premature) tissue and organ aging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses, especially low GSH levels, in younger individuals

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FOLIC ACID is an essential B Group vitamin which is involved in many metabolic processes as an important coenzyme

Luzindole (LUZ) is a widely used non-selective antagonist of the melatonin receptors MT1 and MT2, enabling us to test whether the effects of exogenous melatonin were receptor-mediated (18, 31, 38, 39)