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Vairetti, M

Granada ML, Murillo J, Lucas A, Salinas I, Llopis MA, Castells I, et al

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In cultured adipocytes and several mouse models, 5-Amino-1MQ reduced the NNMT activity marker 1-methylnicotinamide and was associated with changes in adiposity, glucose handling, liver histology and aged-muscle performance

5-Amino-1MQ acts as an NNMT (nicotinamide N-methyltransferase) inhibitor, which is associated with reduced fat storage and improved NAD+ availability

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