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Several limitations could be addressed in future studies
Without a spatially restricted and experimentally identifiable origin of ferroptotic stress, ordered patterns of cell death could simply reflect pre-existing gradients in ferroptosis susceptibility within heterogeneous microenvironments rather than true directional propagation
2026 Enhanced
The appropriate option depends on the patients goals, health history, safety needs, and provider recommendation
These included reductions in functional and cardiovascular age, greater exercise tolerance, and notably lower mortality: treated individuals had 28% fewer deaths overall, about half the cardiovascular mortality, and reduced incidence of heart failure & respiratory disease compared to controls
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