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Our full MOTS-c research guide goes deeper on dosing figures and the metabolic literature

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If you reach day 14 without any perceived benefit at your starting dose, a modest increase to 0.2 mg may be warranted

But pain relief is not the same as tissue healing, and feeling better (also known as the placebo effect) does not always mean an injury is fully repaired

Kidney and cardiovascular outcomes SURPASS-4 kidney composite HR 0.58, slower eGFR decline (-1.4 vs -3.6 mL/min/1.73m2/yr), UACR -6.8% vs +36.9%

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