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In June 2023, Pfizer announced the progress of its oral late-stage glucagon-like peptide-1 receptor agonist (GLP-1-RA) candidate toward first clinical development for the potential treatment of adults with obesity and Type 2 diabetes mellitus (T2DM)
Bourgonje et al., 2021
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That is why controlled trials exist: to separate the product's pharmacological action from everything else
doi:10.3390/ijms22168677
This is because B12 in this form has low bioavailability with absorption typically around ~1-2%
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