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To determine whether glutathione imbalances were capable of sensitizing hepatocytes to TNF-induced cell death, hepatocytes were pretreated with H 2 O 2 (0.1 and 0.2 mM) for 2 h, followed by TNF addition (40 ng/mL)

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Lower levels of GSH were also observed in the substantia nigra of PD patients and the caudate nucleus of progressive supranuclear palsy (PSP) patients 16

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