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Smaller employers, especially those on fully insured plans, have less flexibility and are more cautious due to cost concerns

AMPLITUDE-O compared efpeglenatide to placebo in 4076 adults with T2DM and previous CV events or CV risk factors only [8]

Of those, 20 participants who were high TMAO producers and met all other inclusion criteria progressed to Phase II, with 16 completing the full study (Figure 1)

M., Wood, W

Heres how things compare for average weight loss studies for retatrutide and tirzepatide: Around 3 months: Retatrutide: Not reported Tirzepatide: 8% Around 6 months: 1 year and beyond: Looking at these timelines, you can see that progress doesnt happen all at once

Experts emphasize that there isnt enough evidence to confirm this connection