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Diab Metab Syndr Obes

After seven days of treatment, increases persisted in substantia nigra (both compacta and reticulata), lateral caudate, accumbens nucleus, and superior olive

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Researchers typically aim for a concentration that allows for precise measurement of the 20mg total peptide content

Vanelli M et al

Additionally, further investigations are underway to explore potential additional uses of tirzepatide in the clinical management of other cardiometabolic conditions associated with obesity, including heart failure and non-alcoholic (or metabolic-dysfunction associated) steatohepatitis (NASH/MASH)