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(Biochem Pharmacol, 2001) reported evidence for mechanisms partly separate from classical melanocortin receptor and cAMP signalling

Describing herself as largely 'the lab rat' when she joined the diabetes team, Knudsen remembers she spent 'the first year in a cold room with three technicians to screen hundreds of thousands of compounds to see if they could wedge into the GLP-1 receptor and other targets of interest just snugly enough to stimulate insulin secretion.' To help speed up the screening process, Knudsen devised a method to test 96 candidates in one go instead of just one

[PMID: 2182291] PubMed record related to this compound for laboratory literature review

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