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Keep unopened pens in the refrigerator (28C) but never freeze them Mounjaro: once opened, can be kept at room temperature (below 30C) for up to 21 days Wegovy: once opened, can be kept at room temperature for 11.5 months (as per manufacturer) Avoid keeping them with ice packs or in extreme heat

Lavelle, A

They work by improving insulin sensitivity and, critically, by signaling to the brain that you are full

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A Monday morning shot means you are hitting peak suppression by Tuesday or Wednesday, carrying strong effects through the typical workweek when structured eating is easiest