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Most meaningful weight loss becomes evident after three to four weeks, when cumulative appetite suppression and behavioral changes compound into noticeable physical changes

While these effects are often temporary, they can be significant enough to lead patients to reduce doses, pause treatment, or stop altogether

For diabetes patients, HbA1c is particularly important as it confirms diagnosis and establishes baseline for monitoring improvement

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Supplied as a lyophilized powder, it is reconstituted with bacteriostatic water

Additionally, obese patients have increased circulating plasma volume and lower exercise tolerance with a normal or decreased respiratory reserve