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This is why many dermatologists recommend maintenance doses or the consistent use of sunscreen to preserve the results
This means injections should be administered only by qualified clinicians, and patients need to be fully informed
Melatonin is synthesized in the pineal gland through the activation of two key enzymes: AANAT (arylalkylamine N-acetyltransferase) pCREB (phosphorylated cAMP response element-binding protein) In rat pinealocytes, Epitalon was shown to upregulate both AANAT and pCREB, suggesting a direct enzymatic stimulation of melatonin biosynthesis [56]
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