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In this study, we investigated the underlying cellular mechanisms to decipher how GLP1-R agonists exendin-4 and semaglutide protect the brain in vitro using primary neurons exposed to oxygen-glucose deprivation (OGD) to induce HI, and in vivo where HI was induced by unilateral carotid occlusion in P10 CD1 mice, and either saline, exendin-4 or semaglutide were given immediately after HI
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However, it is still an experimental medication
This patient-led momentum was reinforced by an increase in GLP-1 promotional spend
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