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There is a slightly higher risk of a low blood sugar episode if you combine oral semaglutide with injectable insulin or drugs that trigger insulin secretion (sulfonylureas)

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Minimal side effects have been reported, and may include nausea, abdominal cramps, and diarrhea[6] L-carnitine may increase the effects of blood thinners like Coumadin (warfarin) and Sintrom (acenocoumarol), causing excessive bruising or bleeding