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Engineered bacteria ecn-mt alleviate liver injury in cadmium-exposed mice via its probiotics characteristics and expressing of metallothionein

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121 ChREBP inhibition markedly decreased the expression of L-PK, ACC, and FAS, but restored liver insulin sensitivity by restoring protein kinase B (Akt), and Foxo1 phosphorylation activity with insulin

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10.1126/science.aan3706 99 RowlandI.GibsonG.HeinkenA.ScottK.SwannJ.ThieleI.et al (2018)