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Honeys NSCLC cytotoxic effects have also been associated with its inflammatory cytokine modulation profile (105)

Future investigations employing sequential single-cell transcriptomics, specific inducible gene knockouts, and clinical cohort stratification are urgently needed to elucidate these temporal dependencies, which will pave the way for precise, stage-targeted RCD-modulating therapies in DKD

While high levels of Maillard reaction products can be detrimental, emerging evidence suggests potential hormetic effects of Maillard reaction products (MRPs) at lower doses, primarily stemming from their antioxidant, antimicrobial, and prebiotic properties

Such research models cannot show the full picture of tumor cells in the human development process, so it is necessary to further improve animal experiments or observation of glioma patients in the future

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Tretinoin has been shown to activate the cGAS/STING pathway and inhibit oocyte maturation by inducing mtDNA leakage [309, 310]