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J Biol Chem 284:2500425014 Anello M, Lupi R, Spampinato D et al (2005) Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients

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In summary, IL-6, TNF-, and IL-1 are recognized as key cytokines involved in the pathogenesis of AP, and suppressing their expression can significantly improve the inflammatory microenvironment